RT Journal Article A1 Cigsar Kuzu, Emine Burcu A1 Tiryaki, Sibel A1 Guney, Neslihan A1 Polatdemir, Kamer A1 Cakir, Yasemin A1 Karagozlu Akgul, Ahsen A1 Toper, Muhammed Hasan A1 Karaguzel, Gungor A1 Ucar, Murat A1 Bassorgun, Cumhur Ibrahim A1 Ozel, Seyhmus Kerem A1 Ozkanli, Seyma A1 Salci, Gul A1 Aydin Mungan, Sevdegul A1 Yilmaz, Mehmet Ugur A1 Aytac Vuruskan, Berna A1 Yagmur, Ismail A1 Tarini, Emine Zeynep A1 Kaba, Meltem A1 Tanik, Canan A1 Canbaz, Furkan Adem A1 Hurdogan, Ozge A1 User, Idil Rana A1 Orhan, Diclehan A1 Atici, Ahmet A1 Gursoy, Didar A1 Yagmurlu, Emin Aydin A1 Enneli, Duygu A1 Kilic, Seref Selcuk A1 Erdogan, Seyda T1 Low-Grade Injury following Testicular Torsion: A Multicenter Study Confirming a Disturbing Possibility JF Urologia Internationalis JO Urol Int YR 2023 DO 10.1159/000534454 SP 1 OP 6 SN 0042-1138 AB Introduction: There is an ongoing debate whether to perform orchiectomy or orchidopexy following testicular torsion (TT) in cases where the testis seems non-viable. The main problem is lack of objective criteria defining testicular viability. The aim of this study was to investigate the grade of injury in orchiectomy specimens obtained from cases of TT and its association with clinical findings. Methods: This multicenter retrospective study involved double-blinded reassessment of the patient files and the pathological specimens using Mikuz classification to analyze the relation between clinical and pathological findings. Results: A total of 289 patient charts from 14 centers were reviewed and 228 were included in this study. Twenty (8.8%) patients had grade 1 injury which refers to reversible injury. The clinical findings of these 20 patients were compared to 208 patients with higher grades of injury. As expected, there was statistically significant difference regarding duration of symptoms (p < 0.001); however, range was wide in both groups (as long as 96 h for grade 1 and as short as 7 h for higher grades). There was no statistically significant difference in any other variable including age (median 14 for both, p = 0.531), symptoms (pain: 19/20 vs. 189/202, p = 0.801; swelling: 13/19 vs. 168/197, p = 0.094), absence of blood flow in Doppler US (15/19 vs. 164/197, p = 0.635), or degree of torsion (median 720° for both, p = 0.172). Conclusion: Our study revealed necessity for better criteria to define viability of testis following TT. Histopathological injury appeared to be reversible even in some patients with more severe perioperative findings, late admission, or high degree of twisting. Our findings support the tendency for testicular fixation instead of orchiectomy as none of the clinical or perioperative findings could be attributed to high-grade injury. RD 11/3/2023 UL https://doi.org/10.1159/000534454